Revvity, NET1039250UC, Citalopram, [N-Methyl- H], 250µCi (9.25MBq)

Overview
250 µCi quantity of Citalopram, [N-Methyl-3H]-, is available for your research. Citalopram (Celexa, Cipramil) is a selective serotonin reuptake inhibitor (SSRI) that blocks the serotonin transporter (SERT, 5-HTT). Citalopram is used to treat panic disorder as well as obsessive-compulsive disorder.
We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.
Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NET1039:

Pamela R. Tsuruda, Joey Yung, William J. Martin, Ray Chang, Ngoc Mai, Jacqueline A.M. Smith, Influence of ligand binding kinetics on functional inhibition of human recombinant serotonin and norepinephrine transporters, In Journal of Pharmacological and Toxicological Methods, Volume 61, Issue 2, 2010, Pages 192-204.
Assié, M.-B. and Koek, W. [3H]-8-OH-DPAT binding in the rat brain raphe area: involvement of 5-HT1A and non-5-HT1A receptors. British Journal of Pharmacology, Volume 130, 2000, Pages 1348–1352. Concentration-1 mCi/ml
Molecular Weight-324
Specific Activity-70 - 87 Ci/mmol (2590 - 3219 GBq/mmol)
CAS Number-59729-33-8
Application-Drug Discovery & Development
Brand-NEN Radiochemicals
Buffer/Solvent-Ethanol
Detection Modality-Radiometric
Label Position-Specifically Labeled
Molecular Formula-C20H21FN2O
Packaging-NENSure vial
Radioisotope-3 H
Receptor-Serotonin
Shipping Information-Shipped in dry ice
Shipping Conditions-Shipped in Dry Ice
Special Ordering Information-This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions--20°C
Therapeutic Area-CNS & Neurologic
Unit Size-250 µCi