Revvity, NET1130050UC, Nociceptin, [Leucyl-3,4,5- H], 50µCi (1.85MBq)

Overview
Nociceptin is the endogenous ligand for the nociceptin opioid peptide receptor, and affects numerous brain functions including pain and fear learning.
We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.
Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments. Concentration-0.1 mCi/ml
Molecular Weight-1809.1
Specific Activity-80 - 160 Ci/mmol ( 2960 - 5920 GBq/mmol)
CAS Number-170713-75-4
Application-Drug Discovery & Development
Brand-NEN Radiochemicals
Buffer/Solvent-0.1N acetic acid : ethanol (8:2)
Detection Modality-Radiometric
Label Position-Specifically Labeled
Molecular Formula-C79H129N27O22
Packaging-NENSure vial
Radioisotope-3 H
Receptor-Opioid
Shipping Information-Shipped in dry ice
Shipping Conditions-Shipped in Dry Ice
Special Ordering Information-This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions-5°C
Therapeutic Area-Gastrointestinal Inflammation Metabolic Disorders Pain
Unit Size-50 µCi