Revvity, NET1232250UC, Kainic acid, [Isopropenyl- H]-, 250µCi (9.25MBq)

Overview
250 µCi quantity of Kainic acid, [Isopropenyl-3H]-, is available for your research. Kainic acid (kainate), labeled with tritium (3H) on the isoprenyl group. Kainic acid is a selective agonist for kainate glutamate receptors, which play a role synaptic plasticity. It is a glutamate analog. Common applications include ligand binding assays.
This product replaces NET875001MC.
We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.
Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NET1232:

Honoré T, Davies SN, Drejer J, Fletcher EJ, Jacobsen P, Lodge D, Nielsen FE. Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists. Science (1988) 241 (4866): 701-703. Concentration-1 mCi/ml
Molecular Weight-213.2
Specific Activity->20 Ci/mmol (>740 GBq/mmol)
CAS Number-487-79-6
Application-Drug Discovery & Development
Brand-NEN Radiochemicals
Buffer/Solvent-Ethanol : water (2:98)
Detection Modality-Radiometric
Label Position-Specifically Labeled
Molecular Formula-C10H15NO4
Packaging-NENSure vial
Radioisotope-3 H
Receptor-Glutamate
Shipping Information-Shipped in blue ice
Shipping Conditions-Shipped in Blue Ice
Special Ordering Information-This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions-5°C
Therapeutic Area-CNS & Neurologic
Unit Size-250 µCi