Revvity, NET638250UC, Lysergic Acid Diethylamide, [N-Methyl- H]-, 250µCi (9.25MBq)

Overview
Lysergic Acid Diethylamide (LSD) is a psychedelic drug that acts as an agonist at dopamine D2 receptors and serotonin receptors 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT5A, 5-HT5B and 5-HT6.
We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.
Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NET638:

Teresa Riccioni, Fabio Bordi, Patrizia Minetti, Gilberto Spadoni, Hyung-Mun Yun, Bo-Hye Im, Giorgio Tarzia, Hyewhon Rhim, Franco Borsini, ST1936 stimulates cAMP, Ca2+, ERK1/2 and Fyn kinase through a full activation of cloned human 5-HT6 receptors, In European Journal of Pharmacology, Volume 661, Issues 1–3, 2011, Pages 8-14.
Rigmor Stain-Malmgren, Bengt F Kjellman, Anna Åberg-Wistedt, Platelet serotonergic functions and light therapy in seasonal affective disorder, In Psychiatry Research, Volume 78, Issue 3, 1998, Pages 163-172. Concentration-1 mCi/ml
Molecular Weight-323.4
Specific Activity-60 - 87 Ci/mmol (2220 - 3219 GBq/mmol)
CAS Number-50-37-3
Application-Drug Discovery & Development
Brand-NEN Radiochemicals
Buffer/Solvent-Ethanol
Detection Modality-Radiometric
Label Position-Specifically Labeled
Molecular Formula-C20H25N3O
Packaging-NENSure vial
Radioisotope-3 H
Receptor-5-Hydroxytryptamine
Shipping Information-Shipped in dry ice
Shipping Conditions-Shipped in Dry Ice
Special Ordering Information-This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions--80°C
Therapeutic Area-Cardiovascular CNS & Neurologic Gastrointestinal Inflammation Metabolic Disorders
Unit Size-250 µCi