Revvity, NEX298025UC, MIP-1α (human, recombinant), [ I], 25µCi

Overview
25 µCi Quantities of MIP-1α (human, recombinant), [125I] are available for your research.
We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.
Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NEX298:

Cavallaro, C.L., Briceno, S., Chen, J., Cvijic, M.E., Davies, P., Hynes, J. Jr, Liu, R.Q., Mandlekar, S., Rose, A.V., Tebben, A.J., Van Kirk, K., Watson, A., Wu, H., Yang, G., Carter, P.H. (2012), Discovery and lead optimization of a novel series of CC chemokine receptor 1 (CCR1)-selective piperidine antagonists via parallel synthesis. J Med Chem, 55 (22): 9643-9653. Molecular Weight-~8000
Specific Activity-2200 Ci/mmol (81.4 TBq/mmol)
CAS Number-93474-75-8
Application-Drug Discovery & Development
Brand-NEN Radiochemicals
Buffer/Solvent-Lyophilized
Detection Modality-Radiometric
Fresh Lot Days-Second Monday of each month
Host Species-Human
Label Position-Nominally Labeled
Molecular Formula-C560H890N154O160S8
Packaging-NENSure vial
Radioisotope-125 I
Receptor-Chemokine
Shipping Information-Shipped Ambient
Shipping Conditions-Shipped Ambient
Special Ordering Information-This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions-4°C
Therapeutic Area-Inflammation
Unit Size-25 µCi