Revvity, NEX332005UC, MCP-1,[ I]- labeled, Bolton-Hunter Labeled, 5µCi

Overview
5 µCi Quantities of MCP-1,[125I]- labeled, Bolton-Hunter Labeled are available for your research.
We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.
Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NEX332:

Banisadr, G., Gosselin, R.-D., Mechighel, P., Rostène, W., Kitabgi, P. and Mélik Parsadaniantz, S. (2005), Constitutive neuronal expression of CCR2 chemokine receptor and its colocalization with neurotransmitters in normal rat brain: Functional effect of MCP-1/CCL2 on calcium mobilization in primary cultured neurons. J. Comp. Neurol., 492: 178–192.
Bonini, J.A., Martin, S.K., Dralyuk, F., Roe, M.W., Philipson, L.H., Steiner, D.F. (1997), Cloning, expression, and chromosomal mapping of a novel human CC-chemokine receptor (CCR10) that displays high-affinity binding for MCP-1 and MCP-3. DNA Cell Biol, 16 (10): 1249-1256. Molecular Weight-~8600
Specific Activity-2200 Ci/mmol (81.4 TBq/mmol)
CAS Number-126463-99-8
Application-Drug Discovery & Development
Brand-NEN Radiochemicals
Buffer/Solvent-Lyophilized
Detection Modality-Radiometric
Fresh Lot Days-First Monday of each month
Host Species-Human
Label Position-Nominally Labeled
Packaging-NENSure vial
Radioisotope-125 I
Receptor-Chemokine
Shipping Information-Shipped on Dry Ice
Shipping Conditions-Shipped in Dry Ice
Special Ordering Information-This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions-4°C
Therapeutic Area-CNS & Neurologic Inflammation
Unit Size-5 µCi