Product Description
Overview
25 µCi Quantities of Bombesin (6-14), D-Tyr6[125I] are available for your research.
We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.
Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NEX377:
Liu, J., Lao, Z.J., Zhang, J., Schaeffer, M.T., Jiang, M.M., Guan, X.M., Van der Ploeg, L.H., Fong, T.M. (2002), Molecular basis of the pharmacological difference between rat and human bombesin receptor subtype-3 (BRS-3). Biochemistry, 41 (28): 8954-8960.
Yoshizaki, K., de Bock, V., Solomon, S. (1984), Origin of bombesin-like peptides in human fetal lung. Life Sci, 34 (9): 835-843. Molecular Weight-~1258
Specific Activity-2200 Ci/mmol (81.4 TBq/mmol)
CAS Number-928557-09-7
Application-Drug Discovery & Development
Brand-NEN Radiochemicals
Buffer/Solvent-0.2M NAcetylmethionine, 50mM Phosphoric Acid and 0.25% BSA : 1-propanol (1:1)
Detection Modality-Radiometric
Fresh Lot Days-First Monday of each month
Label Position-Nominally Labeled
Packaging-NENSure vial
Radioisotope-125 I
Receptor-Bombesin
Shipping Information-Shipped on Dry Ice
Shipping Conditions-Shipped in Dry Ice
Special Ordering Information-This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions--20°C
Therapeutic Area-Cancer CNS & Neurologic
Unit Size-25 µCi
Order Guidelines
1. Price & Stock Available on Request. Click to send email to: service@iright.com
2. Please DO NOT make payment before confirmation.
3. Minimum order value of $1,000 USD required.
Collaboration
Tony Tang
Email: Tony.Tang@iright.com
Mobile/WhatsApp/Wechat: +86-17717886924