Revvity, NEX388025UC, Ghrelin (human), [His[ I]], 25µCi

Overview
25 µCi Quantities of Ghrelin (human), [His[125I]] are available for your research.
We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.
Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NEX388:

Gauna, C., van de Zande, B., van Kerkwijk, A., Themmen, A.P., van der Lely, A.J., Delhanty, P.J. (2007), Unacylated ghrelin is not a functional antagonist but a full agonist of the type 1a growth hormone secretagogue receptor (GHS-R). Mol Cell Endocrinol, 274 (1-2): 30-34.
Leung, P.K., Chow, K.B., Lau, P.N., Chu, K.M., Chan, C.B., Cheng, C.H., Wise, H. (2007), The truncated ghrelin receptor polypeptide (GHS-R1b) acts as a dominant-negative mutant of the ghrelin receptor. Cell Signal, 19 (5): 1011-1022. Molecular Weight-3495
Specific Activity-2200 Ci/mmol (81.4 TBq/mmol)
CAS Number-258279-04-8
Application-Drug Discovery & Development
Brand-NEN Radiochemicals
Buffer/Solvent-0.1% trifluroacetic acid and 0.4% BSA : 46% 1-propanol and 54% acetonitrile (1:1)
Detection Modality-Radiometric
Fresh Lot Days-Fourth Monday of each month
Host Species-Human
Label Position-Nominally Labeled
Molecular Formula-C149H249N47O42
Packaging-NENSure vial
Radioisotope-125 I
Receptor-Ghrelin
Shipping Information-Shipped on Dry Ice
Shipping Conditions-Shipped in Dry Ice
Special Ordering Information-This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions--20°C
Therapeutic Area-CNS & Neurologic Obesity
Unit Size-25 µCi