Sartorius, 101000188, FectoVIR®-LV

FectoVIR®-LV is the next generation of transfection reagent, free of animal component, designed to improve LV productivity in HEK-293 cells and made for large scale manufacturing with reduction of the complexation volume and increased complex stability. FectoVIR®-LV benefits allow to increase number of doses produced per batch to treat more patient, while decreasing LV manufacturing costs.

Lentiviral vectors are recognized to be the carrier of choice for allogenic or autologous cell therapies (such as CAR-T) because of its capacity to permanently integrate viral genome into host cell DNA. To produce those vectors, cell therapy producers generally use a transient transfection system that is scaled-up during process development phases. FectoVIR®-LV is the next generation of transfection reagent, free of animal component, designed to improve LV productivity in HEK-293 cell systems. FectoVIR®-LV is made for large scale manufacturing with reduction of the complexation volume and increased complex stability. The FectoVIR®-LV benefits allow to increase number of doses produced per batch to treat more patient, while decreasing LV manufacturing costs.
Take advantage of the complementary DOE service to fast-track optimization of lentivirus production with FectoVIR®-LV.
Key Benefits:
Productivity: Reach the highest Lentiviral vectors titers in suspension systems.
Cost-Effectiveness: Reduce your cost per batch with high titers and low DNA consumption.
Scalability: Produce at large scale with low complexation volume and long complex stability.
Time-Saving: Use DOE service to help you optimizing your process in a record time.

Specifications
Applications:
Application: Lentiviral vectors (LV) manufacturing using HEK-293 derivative cells cultivated in suspension

Biological Information:
Number of transfections: 100 mL of FectoVIR®-LV transfection reagent is sufficient to transfect on average 50 L of cell culture (using standard conditions)

Compliance Information:
Product Documentation: Protocol; Certificate of Analysis; Non-hazardous product statement; Certificate of origin

General Specifications:
Amount of Reagent: FectoVIR®-LV 10 mL

Storage Conditions:
Storage Conditions: 5 °C ± 3 °C