Sartorius, 20270-041, CMM HyperCel - 1 L

CMM HyperCel is a hydrophobic cation exchanger designed for the capture of antibodies, antibody fragments, and recombinant proteins. It allows the separation of proteins with similar pIs and hydrophobicity by modulation of pH and conductivity.
Bulk resins offer flexibility and scalability for large-scale bioprocessing
Allow for customized column packing to meet specific process requirements

CMM HyperCel resin is composed of a rigid cellulose matrix that has flow properties compatible with the needs of manufacturing scale protein production.
The proprietary ligand, containing both a primary amine and a carboxyl group, confers cation exchange and hydrophobicity properties to the chromatography resin. The flexibility of the ligand enables the separation of proteins with a large variety of isoelectric points and hydrophobicity levels, and multiple conditions can be employed to separate targeted molecules from contaminants.
Bulk resins are available in various quantities to support different scaling processes, ensuring flexibility and adaptability. Perfect for large-scale purification processes.
Features and Benefits
Unique selectivity
High capacity mixed-mode chromatography resin
High recovery, low elution volume
Easy CIP, NaOH stable
Applications
Capture of MAbs, Fab fragments and recombinant proteins from challenging feedstocks
Separation of proteins with similar isoelectric point and | or hydrophobicity at low or high conductivity

Specifications
Applications:
Application: Preparative protein purification

Compliance Information:
Quality Standards: CoA; RSF (upon request)

Dimensions:
Bead Size: 50 - 80 µm

General Specifications:
Flow Rate: 100-600cm/h
Resin Format: Bulk resin

Materials of Construction:
Base Matrix: Rigid cellulose beads

Operating Conditions:
Operating Pressure: < 3 barg (44psi)
pH Stability: 1 to 14 (short term), 2 to 13 (long term)

Physicochemical Information:
Ligand: Aminobenzoic acid
Ligand Density: Av. 70 µeq/mL
Reference Protein: Bovine serum albumin (BSA); Human polyclonal IgG
Typical Dynamic Binding Capacity 10% per mL: > 50 mg/mL BSA at pH 4.5, 15 mS/cm; 60-100 mg/mL IgG at pH 4 to 5, 4-12 mS/cm

Product Information:
Brand: CMM HyperCel
Pack Size: 1
Pack Volume: 1 L
Resin Type: Mixed Mode cation exchanger
What you receive: 1 bottle resin, instructions

Storage Conditions:
Storage Conditions: 20% EtOH/1M NaCl