Thermo Fisher, 22324, Sulfo-GMBS (N-γ-maleimidobutyryl-oxysulfosuccinimide ester)

Sulfo-GMBS (N-γ-maleimidobutyryl-oxysulfosuccinimide ester) Thermo Scientific Pierce Sulfo-GMBS is a water-soluble amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short spacer arm (7.
3 angstroms).
Features of Sulfo-GMBS:
•Reactive groups:sulfo-NHS esterandmaleimide
•Reactive towards: amino and sulfhydryl groups
• Non-cleavable
• Water-soluble (compare toGMBS)
• Has a low potential for illiciting crosslinker immune response, ensuring that the primary response to the antigen-carrier protein conjugate is not diluted by a response against a determinant on the crosslinker
• GMBS and Sulfo-GMBS are reported to be less immunogenic thanSMCCProduct References:Crosslinker Application Guide -- search for recent literature references for this productCell Permeability: No
Description: Sulfo-GMBS
Form: Powder
Labeling Method: Chemical Labeling
Molecular Weight (g/mol): 382.
28
PEGylated: No
Product Line: Pierce™
Quantity: 50 mg
Reactive Moiety: Maleimide, Sulfo-NHS Ester
Shipping Condition: Ambient
Solubility: Water
Spacer Arm Length: 7.
3 Å
Water Soluble: Yes
Chemical Reactivity: Amine-Sulfhydryl
Cleavable: No
Crosslinker Type: Heterobifunctional
Format: Standard
Product Type: Crosslinker
Spacer: Short (<10 Å)
Unit Size: Each