Thermo Fisher, 23011, Pierce™ MMTS (methyl methanethiosulfonate)

Pierce™ MMTS (methyl methanethiosulfonate) Thermo Scientific Pierce MMTS (methyl methanethiosulfonate) is a small compound that reversibly blocks cysteines and other sulfhydryl groups, enabling the study of enzyme activation and other protein functions.
Features of MMTS (methyl methanethiosulfonate):
• Converts sulfhydryl groups on cysteine side chains into -S-S-CH3
• Reaction is reversible with DTT or TCEP, restoring the free sulfhydryl
• Used to modify thiol groups in creatine kinaseMMTS (methyl methanethiosulfonate) is a sulfhydryl-reactive compound that can reversibly sulfenylate thiol-containing molecules. Reacting MMTS with reduced sulfhydryls (-SH) results in their modification to dithiomethane (-S-S-CH3). Treatment with reducing agents, such as dithiothreitol (DTT), 2-mercaptoethanol (2-ME) or Tris(2-carboxyethyl) phosphine hydrochloride (TCEP), will cleave the disulfide groups to restore the original sulfhydryl. MMTS is commonly used to study biochemical pathways involving thiol-dependent enzymes.
More Product Data
•Specific labeling, enrichment and quantitation of S-nitrosylated peptides using iodoTMT reagentsForm: Liquid
Label Type: Blocking Groups
Label or Dye: Unreactive Group
Product Line: Pierce™
Quantity: 200 mg
Reactive Moiety: Thiol
Chemical Reactivity: Thiol
Product Type: Methyl Methanethiosulfonate
Unit Size: Each