Thermo Fisher, 23013, SPB (succinimidyl-[4-(psoralen-8-yloxy)]-butyrate)

SPB (succinimidyl-[4-(psoralen-8-yloxy)]-butyrate) Thermo Scientific Pierce SPB is an NHS-ester and psoralen crosslinker that effectively conjugates primary amines to DNA via light-activated intercalation next to pyrimidine bases.
Features of SPB:
•Reactive groups:NHS esterandpsoralen
•Reactive toward: amino groups and thymine
• DNA intercalating agent and nucleic acid probe1,2
• Reagent for photo-immobilization to microplates3
• Melting point: 177-178°CProduct References:Crosslinker Application Guide -- search for recent literature references for this productCell Permeability: Not determined
Description: SPB
Form: Solid
Labeling Method: Chemical Labeling
Molecular Weight (g/mol): 385.
32
PEGylated: No
Product Line: Pierce™
Quantity: 50 mg
Reactive Moiety: Psoralen, NHS Ester
Shipping Condition: Ambient
Solubility: DMF, DMSO
Spacer Arm Length: 8.
6 Å
Water Soluble: No
Chemical Reactivity: Amine-Nonselective
Cleavable: No
Crosslinker Type: Heterobifunctional
Format: Standard
Product Type: Crosslinker
Spacer: Short (<10 Å)
Unit Size: Each