Thermo Fisher, 24500, NHS (N-hydroxysuccinimide) Thermo Scientific™

NHS (N-hydroxysuccinimide) Thermo Scientific™ Thermo Scientific Pierce NHS is a chemical modification reagent for converting carboxyl groups to amine-reactive NHS esters for bioconjugation, crosslinking, labeling and immobilization methods.
Features of NHS:
• Efficiency of EDC-mediated coupling is increased in the presence of NHS
• Amine-reactive NHS esters can be made with any carboxyl-containing molecule
• NHS derivatives of typical small molecules (e.
g., biotin) are uncharged, organic-soluble (dissolve first in DMSO) and cell membrane-permeable
• High-purity, crystalline NHS can be used to create high-quality activated derivativesNHS (N-hydroxysuccinimide), the uncharged analog of Sulfo-NHS (N-hydroxysulfosuccinimide), enables control and modification of carbodiimide crosslinking reactions involving activation of carboxylates (—COOH) for conjugation with primary amines (—NH2).
Product References:Crosslinker Application Guide -- search for recent literature references for this productCell Permeability: Not determined
Description: NHS
Form: Powder
Labeling Method: Chemical Labeling
Molecular Weight (g/mol): 115.
09
PEGylated: No
Product Line: Pierce™
Quantity: 25 g
Reactive Moiety: Carbodiimide
Shipping Condition: Ambient
Solubility: Water
Water Soluble: Yes
Chemical Reactivity: Amine-Carboxyl
Cleavable: No
Crosslinker Type: Heterobifunctional
Format: Standard
Product Type: Crosslinker
Spacer: Short (<10 Å)
Unit Size: Each