Thermo Fisher, 27-1823-11, 2'-OMe-Ac-C Phosphoramidite, standard grade, 28-400 finish bottle

Thermo Fisher, 27-1823-11, 2'-OMe-Ac-C Phosphoramidite, standard grade, 28-400 finish bottle 2'-OMe-Ac-C CEP is a phosphoramidite containing 5' DMT and the nucleoside cytidine (C) with 2'-O-methyl protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methyl (OMe) oligo modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 30-mL amber bottle with a 28-400 finish neck style, which is compatible with most MerMade synthesizers.
Features:
• HPLC purity—≥98.
0%; Sum of PIII impurities (140-152ppm) ≤0.
5%31P NMR Purity: ≥98%
CAS: 199593-09-4
Chemical Name or Material: 5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-O-methyl-cytidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Description: Base: CBase Protection: Ac
For Use With (Application): Oligonucleotide synthesis
For Use With (Equipment): MerMade Synthesizers
Form: Powder
Format: Amber bottle (28-400 finish neck style)
Grade: Standard
Molecular Formula: C42H52N5O9P
Molecular Weight (g/mol): 801.
86 g/mol
Nucleic Acid Type: RNA
Nucleoside Type: Cytidine (C)
Product Type: 2in-OMe-Ac-C CEP
Purity: ≥98% (HPLC)
Quantity: 1 g
Reagent Features: 2in-OMe modified, Fast deprotection
Reagent Type: Phosphoramidite
Shipping Condition: Room Temperature
Unit Size: Each