Thermo Fisher, 901843, Axiom™ Genome-Wide CHB 1 & CHB 2 Array Set Bundle

Axiom™ Genome-Wide CHB 1 & CHB 2 Array Set Bundle Axiom Genome-Wide Population-Optimized Human Arrays are genotyping panels that offer the best genetic coverage of rare and common variants for genome-wide disease association studies.
The Axiom Genome-Wide CHB 1 and CHB 2 Array Set Bundle contains the Axiom Genome-Wide CHB 1 Array Plate and the Axiom Genome-Wide CHB 2 Array Plate. The Axiom Genome-Wide CHB 1 Array Plate maximizes genomic coverage of common alleles (MAF >5%) of the Han Chinese genome. The Axiom Genome-Wide CHB 2 Array Plate is designed to target rare variants (MAF 2-5%) as a complement to Axiom Genome-Wide CHB 1 Array Plate. The Axiom Genome-Wide CHB 1 and CHB 2 Array Set Bundle enables the most comprehensive commercially available genome-wide coverage in CHB populations.
Benefits of Axiom Genome-Wide Population-Optimized ArraysEach array plate was designed to achieve ˜90% genomic coverage (r2>0.
8) in each target population, while covering markers with MAF of 1-5% in areas such as:
• Critical biological categories (e.
g., coding SNPs)
• Biological processes (e.
g., drug metabolizing genes)
• Disease categories (e.
g., cardiovascular disease, cancer, immunity/inflammation, MHC, and CNS)
• Common and rare SNPs and insertions/deletions (indels) from the International HapMap Project, 1000 Genomes Project, and published disease associations
• Genotype-tested genomic content proven to give informative and reliable results
• Markers preselected for coverage in critical biological categories, such as coding SNPs, and biological pathways, such as drug metabolizing or cardiovascular genes
• High sample pass rate, call rate, and reproducibility
• Compatible with the Axiom 2.
0 Reagent Kit, GeneTitan™ MC Instrument, automated or manual workflow, and Genotyping Console™ SoftwareOther Maximum Genome-Wide Coverage ArraysThese array plates are designed to maximize whole-genome coverage of common and rare alleles, including SNPs within 10 kb of genes.
•Axiom Genome-Wide CEU 1 Array Plate- The first cost-effective array to maximize coverage of rare variants (MAF >1%) for European populations
•Axiom Genome-Wide ASI 1 Array Plate- The first array designed to maximize genomic coverage of rare alleles (MAF >1%) of a consensus East Asian (JPT+CHB) genome
•Axiom Genome-Wide PanAFR Array Plate Set- The first array to offer pan-African genomic coverage, with ≥90% genetic coverage of common and rare variants (MAF >2%) of the Yoruba (West African) genome and >85% coverage of common and rare variants (MAF >2%) of the Luhya and Maasi (East African) genomes. This array set also offers high genomic coverage (>85%) in admixed populations with West African ancestry.
Please visit ourNetAffx Analysis Centerfor more information on microarray analysisDon't see what you're looking for? Learn how tocreate an Axiom myDesign™ Array Platetailored for your study.
Required ProductsAxiom Analysis SuiteGeneChip Command Console SoftwareGeneTitan Multi-Channel InstrumentFor Use With (Application): Microarray Analysis
Quantity: 1 plate
Array: Genotyping
Format: 96-array Plate
Number of Arrays: 96 arrays
Species: Maize
Unit Size: Each