Thermo Fisher, 902106, Axiom™ Exome 319 Array Plate

Axiom™ Exome 319 Array Plate Streamline your causal variant studies by enriching genome-wide association studies (GWAS) datasets with an extensive set of novel, rare, putative functional variants. The content was discovered in 16 major exome sequencing projects spanning a total of 12,000 samples.
With the Axiom Exome 319 Array Plate, you get:
•Comprehensive content for highest discovery power- More than 300,000 coding SNPs including non-synonymous and synonymous SNPs as well as variants in splice and stop codons.- Approximately 30,000 single-base and complex indels from the draft Phase 1 1000 Genomes Project exome calls.
•Informative markers to enable integrated data analysis- AIMs: Ancestry informative markers to measure Latino and African American ancestry. All markers have low linkage disequilibrium (LD) and span all autosomes and chromosome X.- >GWAS tags: Includes over 5,000 SNPs reported in the NHGRI Catalog of Published Associations (August 2011) and additional unpublished hits from scientific collaborations.- High value: Contains other markers of interest, including DNA fingerprinting SNPs, human leukocyte antigen (HLA) genes, chromosome Y, mitochondrial DNA, and microRNA sequences.
•Customization to include your candidate genes- Include an additional 100,000 SNPs from your own candidate genes to meet your research needs. Choose from the Axiom Genomic Database of 11M genotype-tested markers, or include variants of your own choosing.
•Proven performance- The panel has been fully genotype-tested against stringent QC criteria to ensure high-quality data.- Every marker has been tested against approximately 1,200 samples to ensure high sample pass, call rate, and reproducibility.
Axiom Exome Genotyping Array Plates include:-Axiom 2.
0 Reagent Kitfor automated or manual processing of up to 96 samples per array plate.- A fully automated workflow with validated robotics methods for target preparation and array processing, based on the Beckman Biomek™ FXP Target Prep Express System and theGeneTitan™ MC Instrument.- A manual target preparation protocol for lower-throughput users.-Axiom Analysis Suitefor automated allele calling and easier quality assessment of called genotypes.
Required ProductsAxiom Analysis SuiteGeneChip Command Console SoftwareGeneTitan Multi-Channel InstrumentFor Use With (Application): Microarray Analysis
Quantity: 1 plate
Array: Genotyping
Format: 96-array Plate
Number of Arrays: 96 arrays
Species: Human
Unit Size: 1 plate