Thermo Fisher, A33545, DSBU (Disuccinimidyl Dibutyric Urea)

DSSO Chemical crosslinking in combination with mass spectrometry is a powerful method to improve protein characterization and identification of protein-protein interactions. This method has been applied to recombinant and native protein complexes and, more recently, to whole cell lysates or intact unicellular organisms in efforts to identify protein-protein interactions on a global scale. The more recent enhancement of cleavability in DSSO and DSBU has improved MS compatibility and sensitivity of detection of crosslinked peptides and proteins.
Cell Permeability: Yes
Description: DSSO
Form: Powder
Labeling Method: Chemical Labeling
Molecular Weight (g/mol): 388.
35
PEGylated: No
Quantity: 10 x 1 mg
Reactive Moiety: NHS Ester
Solubility: DMF, DMSO
Spacer Arm Length: 10.
3 Å
Water Soluble: No
Chemical Reactivity: Amine-Amine
Cleavable: By CID using MS
Crosslinker Type: Homobifunctional
Format: Standard, Single-use
Product Type: Crosslinker
Spacer: Medium (10 to 30 Å)
Unit Size: Each