Thermo Fisher, A53359, POROS™ CaptureSelect™ ClusterinClear Affinity Resin

250 mL POROS CaptureSelect ClusterinClear Affinity Resin is specifically designed for efficient clearance of clusterin through affinity capture. Clusterin is identified as a notorious host cell protein (HCP) contaminant in the downstream process of biotherapeutics expressed in CHO cells, such as monoclonal antibodies and Fc-fusion constructs. Therefore, implementing a clusterin-specific polishing step in flow-through mode, after the primary capture, can adequately remove this contaminant and its complexes while the recombinant protein is untouched.
Binding Capacity: >8 mg/mL
Matrix: Cross-linked poly(styrene-divinylbenzene)
Shipping Condition: Wet Ice
Particle Size: 50 μm
Form: Resin Slurry
Product Line: POROS™ CaptureSelect™
Quantity: 250 mL
Type: Resin
Ligand Type: Single-domain [VHH] antibody fragment
Unit Size: Each