Product Description
Thermo Fisher, C481, Calcein AM, cell-permeant green and blue dyes Calcein AM is a cell-permeant dye frequently used in cell biology research. It is derived from Calcein, a fluorescent dye that exhibits bright green fluorescence upon binding to intracellular free calcium ions. Calcein AM is a non-fluorescent compound that can permeate the cell membrane due to its lipophilic properties. Once inside the cell, it is cleaved by intracellular esterases, yielding the fluorescent Calcein molecule. This conversion allows the dye to be retained within the cytoplasm; apoptotic and dead cells with compromised membranes do not retain Calcein.
Cell Permeability: Cell-impermeant
Dye Type: Other Label(s) or Dye(s)
Quantity: 100 mg
Reagent Type: Cell Tracker Compounds, Cell Labeling Reagents
Shipping Condition: Room Temperature
Emission: 517
Excitation Wavelength Range: 494 nm
For Use With (Application): Cell Tracing, Cell Tracker
For Use With (Equipment): Fluorescence Microscope
Product Type: Calcein, high purity
Unit Size: Each
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