Product Description
Thermo Fisher, F13192, Fibrinogen From Human Plasma, Alexa Fluor™ 546 Conjugate Molecular Probes™ fibrinogen conjugates are prepared by attaching fluorescent dye molecules to purified human fibrinogen (approximately 15 dye molecules for each fibrinogen molecule), purifying the conjugate to remove unreacted dye, and then lyophilizing for storage.
Fluorescently labeled fibrinogen has proven to be a valuable tool for investigating platelet activation and subsequent fibrinogen binding. For instance, fluorescein-labeled fibrinogen has been used to detect fibrinogen bound to activated platelets by flow cytometry.
Human Fibrinogen Conjugate Specifications:
• Label (Ex/Em): Alexa Fluor™ 546 (∼558/573 nm)
• Spectrally similar to tetramethylrhodamine (TMR), but is brighter and more photostable
• Lyophilized product can be dissolved in buffer (e.
g., sodium bicarbonate, pH 8.
3) for use
• Fluorescence is typically detected using fluorescence microscopy or flow cytometryFind More Probes for Cell Adhesion and Receptor BindingReviewProbes for Cell Adhesion, Chemotaxis, Multidrug Resistance and Glutathione—Section 15.
6andProbes for Following Receptor Binding and Phagocytosis—Section 16.
1in the Molecular Probes™ Handbook for more information on these probes.
For Research Use Only. Not for human or animal therapeutic or diagnostic use.
Label Type: Alexa Fluor Dyes
Product Line: Alexa Fluor™
Protein Subtype: Fibrinogen
Quantity: 5 mg
Shipping Condition: Room Temperature
Conjugate: Alexa Fluor 546
Form: Lyophilized
Species: Human
Unit Size: Each
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