Thermo Fisher, PV5365, Predictor™ hERG Fluorescence Polarization Assay Kit

Predictor™ hERG Fluorescence Polarization Assay Kit The Predictor™ hERG Fluorescence Polarization Assay Kit provides a set of validated components to perform hERG channel biochemical binding studies in the absence of radioligand. The assay was designed to identify potential hERG channel blockers by producing data that accurately correlates with patch-clamp electrophysiology studies. The assay is based on the principle of fluorescence polarization where a red-shifted fluorescent tracer is displaced from the hERG channel by compounds that bind to the channel. Assay performance was validated with a panel of established hERG channel blockers. Results from the Predictor™ assay demonstrate a high correlation with those obtained from patch clamp techniques.
Assay Entry: Biochemical binding
Color: Red
Detection Method: Fluorescence
Druggable Target: Ion Channels
For Use With (Equipment): Microplate Reader
Gene Symbol: hERG
Packaging: 384-well Plate
Product Type: Assay Kit
Protein Family: Ion Channels
Quantity: 1 Kit
Readout: End Point
Shipping Condition: Dry Ice
System Type: Predictor™ System
Target Entry: hERG
Conjugate: Predictor hERG Tracer Red
Product Line: Predictor™
Unit Size: Each