Waters, 186008947, BioResolve RP mAb Polyphenyl VanGuard Cartridge, 450Å, 2.7 µm, 3.9 mm X 5 mm, 3/pk

BioResolve RP mAb Polyphenyl VanGuard Cartridge, 450Å, 2.7 µm, 3.9 mm X 5 mm Columns contain 2.7 µm superficially-porous-silica particles having an average pore diameter of 450Å. The particles are functionalized with a proprietary polyphenyl bonding process that was specifically designed for LC or LC-MS analyses of intact IgG monoclonal antibodies and their fragments. This Part Number contains (3) VanGuard Cartridges. Note: The VanGuard Universal Cartridge Holder (p/n: 186007949) is required for use with these replaceable cartridges. p/n: 176004161 contains (3), 3.9 x 5mm VanGuard Cartridges as well as an included VanGuard Universal Cartridge Holder (p/n: 186007949). This guard column is compatible with: p/n: 186008953 BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 50 mm p/n: 186008954 BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 100 mm p/n: 186008955 BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 150 mm p/n: 176004167 BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 50 mm w/ Standards p/n: 176004168 BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 100 mm w/ Standards p/n: 176004169 BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 150 mm w/ Standards

Specifications
Separation Mode: Reversed Phase
Temperature Limits: 90 C
Maximum Pressure: 10000 psi (689 Bar)
Particle Size: 2.7 µm
Pore Size: 450 Å
QC Tested: Protein
System: HPLC, UHPLC, UPLC
USP Classification: L11
UNSPSC: 41115709
Product Type: Guards

Additional Information
BioResolve RP mAb Polyphenyl VanGuard Cartridge Engineered for scientists working at the forefront of biopharmaceutical analysis, the BioResolve RP mAb Polyphenyl VanGuard Cartridge (450Å, 2.7 µm, 3.9 mm x 5 mm) is purpose-built to enhance the robustness and lifetime of BioResolve RP mAb Polyphenyl analytical columns. Each cartridge contains superficially porous silica particles with a large 450Å pore size, ideal for intact monoclonal antibody (mAb) and fragment separations. These particles are bonded with a proprietary polyphenyl ligand, optimized for reversed-phase LC and LC-MS workflows targeting IgG mAbs and their subunits. This part number includes three VanGuard guard cartridges. To operate them effectively, you'll need the BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 2.1 mm X 150 mm, 1/pk , designed for direct analytical applications. Ready to upgrade your protein separations? Shop Waters lab equipment built for biopharma precision. FAQs about the BioResolve RP mAb VanGuard Cartridge What does this VanGuard cartridge protect? This guard cartridge is designed to sit in front of your main analytical column and trap particulates or contaminants before they reach the column, helping to extend its lifespan and maintain analytical performance. Can I use this guard cartridge for LC-MS analysis? Yes. It is specifically engineered with a polyphenyl bonded phase for compatibility with reversed-phase LC and LC-MS workflows, especially those involving intact monoclonal antibodies and fragments.